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Showing posts with label Shyamsunder Panchavati. Show all posts
Showing posts with label Shyamsunder Panchavati. Show all posts

Thursday, September 27, 2018

Gut Branches of Vagus Nerve Essential Components of Brain’s Reward and Motivation System 09-27





Summary: Researchers report a gut-brain neural circuit establishes the vagus nerve as an essential component of the brain system that regulates reward and motivation. 


A novel gut-to-brain neural circuit establishes the vagus nerve as an essential component of the brain system that regulates reward and motivation, according to research conducted at the Icahn School of Medicine at Mount Sinai and published September 20 in the journal Cell. The study provides a concrete link between visceral organs and brain function, especially in regards to reward, and may help to inform novel targets for vagal stimulation therapy, particularly for eating and emotional disorders.

Previous research established the gut as a major regulator of motivational and emotional states but until now, the relevant gut-brain neuronal circuitry remained elusive. The vagus nerve, the longest of the cranial nerves, contains motor and sensory fibers and passes through the neck and thorax to the abdomen. Traditionally, scientists believed that the nerve exclusively mediated suppressive functions such as fullness and nausea; in contrast, circulating hormones, rather than vagal transmission, were thought to convey reward signals from the gut to the brain.

“Our study reveals, for the first time, the existence of a neuronal population of ‘reward neurons’ amid the sensory cells of the right branch of the vagus nerve,” says Ivan de Araujo, DPhil, Senior Faculty in the Department of Neuroscience at the Icahn School of Medicine at Mount Sinai and senior author of the paper. “We focused on challenging the traditional view that the vagus nerve is unrelated to motivation and pleasure and we found that stimulation of the nerve, specifically its upper gut branch, is sufficient to strongly excite reward neurons lying deep inside the brain.”

The branches of the vagus nerve are intricately intermingled, making it extremely difficult to manipulate each organ separately. To address this challenge, the research team employed a combination of virally delivered molecular tools that allowed them to exclusively target the vagal sensory neurons connected to the stomach and upper intestine.

Specifically, researchers combined different viruses carrying molecular tools in a way that allowed them to optically activate vagal neurons connected to the gut while vagal neurons leading to other organs remained mute. The approach, a state-of-the-art technique known as “optogenetics,” allows investigators to use light to manipulate the activity of a prespecified set of neurons. 

The study revealed that the newly identified reward neurons of the right vagus nerve operate under the same constraints attributed to reward neurons of the central nervous system, meaning they link peripheral sensory cells to the previously mapped populations of reward neurons in the brain. Strikingly, neurons of the left vagus were associated with satiety, but not with reward. The research team’s anatomical studies also revealed, for the first time, that the right and left vagal branches ascend asymmetrically into the central nervous system.

“We were surprised to learn that only the right vagal branch eventually contacts the dopamine-containing reward neurons in the brainstem,” explained Wenfei Han, MD, PhD, Assistant Professor of Neuroscience at the Icahn School of Medicine at Mount Sinai and lead author of the study. Dopamine is a neural transmitter known to be essential for reward and motivation. 

The uncovering of right gastrointestinal vagal neurons as conveyors of reward signals to the brain opens opportunities for novel, more specific stimulation targets that may increase the efficacy of vagal nerve stimulation therapy, a treatment that involves delivering electrical impulses to the vagus nerve, for patients suffering from emotional and eating disorders. 





Wednesday, April 11, 2018

Manmohan Singh donates 3,500 books from his personal library to his alma mater 04-12


India's former Prime Minister Dr Manmohan Singh has donated 3,500 books from his personal collection to his alma mater Panjab University (PU).



According to university authorities, the arrangements would soon be made to transport books and memorabilia, photographs and paintings from New Delhi to the university campus.
As per the IANS report, the books and other objects will be kept in the Guru Teg Bahadur Bhawan on the university campus.

Here's what the professor of Department of History told IANS:

"The 3,500 books and memorabilia, which include photographs and paintings, will be housed in Guru Teg Bahadur Bhawan. Until the place is ready for the installation, books and memorabilia will be kept in the main library," she said.
"It will be developed as a library where there would be a reading area where anybody can come and have a look at the material," she added.

India's former Prime Minister Dr Manmohan Singh has donated 3,500 books from his personal collection to his alma mater Panjab University (PU).
According to university authorities, the arrangements would soon be made to transport books and memorabilia, photographs and paintings from New Delhi to the university campus.
As per the IANS report, the books and other objects will be kept in the Guru Teg Bahadur Bhawan on the university campus.

Here's what the professor of Department of History told IANS:

"The 3,500 books and memorabilia, which include photographs and paintings, will be housed in Guru Teg Bahadur Bhawan. Until the place is ready for the installation, books and memorabilia will be kept in the main library," she said.
"It will be developed as a library where there would be a reading area where anybody can come and have a look at the material," she added. 



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Wednesday, January 31, 2018

Robocop Ford is developing a robot police car 01-31




robocop

Ford is developing a robot police car to catch speeding drivers and slap them with fines. 



The car giant has been issued with a patent for the artificial intelligence tech that will catch motorists breaking road laws.

The sketches filed with the US Patent & Trademark Office even show the sneaky Robocop hiding behind a tree.
Cameras and wireless sensors will allow it to track cars and connect over wifi to let them know they've broken the law.
The regular car would then message back revealing if it was in driverless mode - or with the driving licence photo of the person in control.
Robocop could then issue a warning or fine remotely.




The robotic cop car will be fitted with cameras and wifi allowing it to be used as a remote surveillance device - or to call in back up.
And the patent reveals it can even drive itself to hunt down rogue motorists - or be used with an officer inside.
The Ford patent said: "While autonomous vehicles can and will be programmed to obey traffic laws, a human driver can override that programming to control and operate the vehicle at any time.
"When a vehicle is under control of a human driver there is a possibility of violation of traffic laws. Thus, there will still be a need to police traffic.

"An autonomous police vehicle may enforce traffic laws by identifying violators, pulling over the offending vehicle, capturing an image of the licence plate of the offending vehicle, and determining whether to issue a warning or a ticket.
“Autonomous police vehicle may be trained or otherwise programmed using machine learning tools – deep neural networks – to find good hiding spots to catch violators of traffic laws.”
The futuristic tech is still some way off but the very fact Ford has filed a patent means it's on their radar.
It mimics the sci-fi cop cars seen in Sylvester Stallone's 1993 cult classic Demolition Man - plus the iconic 80s action star Robocop.

Computational astrophysics team uncloaks magnetic fields of cosmic events 01-31





The development of ultra-intense lasers delivering the same power as the entire U.S. power grid has enabled the study of cosmic phenomena such as supernovae and black holes in earthbound laboratories. Now, a new method developed by computational astrophysicists at the University of Chicago allows scientists to analyze a key characteristic of these events: their powerful and complex magnetic fields.


In the field of high-energy density physics, or HEDP, scientists study a wide range of astrophysical objects—stars, supermassive black holes at the center of galaxies and galaxy clusters—with laboratory experiments as small as a penny and lasting only a few billionths of a second. By focusing powerful lasers on a carefully designed target, researchers can produce plasmas that reproduce conditions observed by astronomers in our sun and distant galaxies.


Planning these complex and expensive experiments requires large-scale, high-fidelity computer simulation beforehand. Since 2012, the Flash Center for Computational Science of the Department of Astronomy & Astrophysics at UChicago has provided the leading open computer code, called FLASH, for these HEDP simulations, enabling researchers to fine-tune experiments and develop analysis methods before execution at sites such as the National Ignition Facility at Lawrence Livermore National Laboratory or the OMEGA Laser Facility in Rochester, N.Y.


"As soon as FLASH became available, there was kind of a stampede to use it to design experiments," said Petros Tzeferacos, research assistant professor of astronomy and astrophysics and associate director of the Flash Center.


During these experiments, laser probe beams can provide researchers with information about the density and temperature of the plasma. But a key measurement, the magnetic field, has remained elusive. To try and tease out magnetic field measurements from extreme plasma conditions, scientists at MIT developed an experimental diagnostic technique that uses charged particles instead, called proton radiography.


In a new paper for the journal Review of Scientific Instruments, Flash Center scientists Carlo Graziani, Donald Lamb and Tzeferacos, with MIT's Chikang Li, describe a new method for acquiring quantitative, high-resolution information about these magnetic fields. Their discovery, refined using FLASH simulations and real experimental results, opens new doors for understanding cosmic phenomena.
"We chose to go after experiments motivated by astrophysics where magnetic fields were important," said Lamb, the Robert A. Millikan Distinguished Service Professor Emeritus in Astronomy & Astrophysics and director of the Flash Center. "The creation of the code plus the need to try to figure out how to understand what magnetic fields are created caused us to build this software, that can for the first time quantitatively reconstruct the shape and strength of the magnetic field."
Skyrocketing experiments
In proton radiography, energetic protons are shot through the magnetized plasma towards a detector on the other side. As the protons pass through the magnetic field, they are deflected from their path, forming a complex pattern on the detector. These patterns were difficult to interpret, and previous methods could only make general statements about the field's properties.
"Magnetic fields play important roles in essentially almost every astrophysical phenomena. If you aren't able to actually look at what's happening, or study them, you're missing a key part of almost every astrophysical object or process that you're interested in," said Tzeferacos.
By conducting simulated experiments with known magnetic fields, the Flash Center team constructed an algorithm that can reconstruct the field from the proton radiograph pattern. Once calibrated computationally, the method was applied to experimental data collected at laser facilities, revealing new insights about astrophysical events.
The combination of the FLASH code, the development of the proton radiography diagnostic, and the ability to reconstruct magnetic fields from the experimental data, are revolutionizing laboratory plasma astrophysics and HEDP. "The availability of these tools has caused the number of HEDP experiments that study magnetic fields to skyrocket," said Lamb.
The new software for magnetic field reconstruction, called PRaLine, will be shared with the community both as part of the next FLASH code release and as a separate component available on GitHub. Lamb and Tzeferacos said they expect it to be used for studying many astrophysics topics, such as the annihilation of magnetic fields in the solar corona; astrophysical jets produced by young stellar objects, the Crab Nebula pulsar, and the supermassive black holes at the center of galaxies; and the amplification of magnetic fields and acceleration of cosmic rays by shocks in supernova remnants.
"The types of experiments HEDP scientists perform now are very diverse," said Tzeferacos. "FLASH contributed to this diversity, because it enables you to think outside the box, try different simulations of different configurations, and see what plasma conditions you are able to achieve."

Monday, January 29, 2018

How to Build an Employee Experience That Rivals Your Customer Experience 01-29





Image credit :  Shyam's Imagination Library.

The marketing landscape is evolving rapidly. Hardly breaking news. There are new companies and
products constantly popping up that enable more efficient and effective work across all channels. The teams that achieve the most success are the ones that are constantly up-to-date with these new tools.

Finding new products is also a lot easier today than it was in the past. Today, there are far more thought leaders, newsletters, and blogs sharing the latest trends and ways in which companies are taking advantage of them.

Moving forward, the landscape is going to continue to morph and expand, which is truly saying something when you consider the number of martech options that were available in 2017 as per Scott Brinker's infamous chart. And if you can't read it here, and who can blame if you can't, you can see the full version here.

Here are 5 ways that tech is going to change marketing in 2018 that you should be on the lookout for:

1. It Will Be Easier To Find Customers

There are inbound leads, like site visitors, and there are also outbound leads, like a group of Sales VPs that get sent an email. Tech is making it easier to find and sell to both of these groups.
For inbound, technology has enabled marketing teams to find out more about their website visitors. Companies can run reverse IP lookups to match a visitor with the company they work for. Different services are also making it easier to capture emails. Emails are more valuable than ever because enrichment products can tell you everything about a person once given an email. Plus, that data is becoming more accurate as time goes on.

Outbound leads have also become easier to find. Marketing teams can take advantage of lead generation services that offer unique targeting of
audiences. The customization that companies will be able to do to gather leads, and the quality of those leads, will also increase in 2018. This is, consequently, enabling companies to spend more time figuring out who their target audience is, instead of actually gathering their information.

2. There Is Better Customization

Once you know the visitor's title, location, company and/or industry, anything about their site experience can be changed. This could be the images they are presented, the customers or testimonials they see for social proof, and even the messages sent by a chatbot. This customization, and the functionality for it, is going to improve dramatically in 2018.

The early movers are also going to get a huge bump in conversion rates. They will be able to target messaging and pictures to fit the psyche of each company and visitor. Instead of needing a catch-all site, companies can segment their audiences. Mark Rabe, SVP of Art Concrete Solutions told me, “We have 2 very different customers. One group are potential franchisees for our concrete repair business. The other group are consumers who might purchase our DIY concrete repair bucket. We have to segment our visitors and show them relevant info or they’re gone fast. We can display the best option given data we have on the visitor. That, inevitably, will increase conversion rates.”

3. There Will Be A Greater Push For Immediate Sales

People have many distractions today, and that will only increase in 2018. They are constantly flooded with emails and content, as well as spend a significant amount of time on social media. Therefore, in 2018, marketing is going to move further towards quick sales. E-commerce sites are trying to capture the sale upon a user’s first visit. They are already offering discounts for immediate buys and will likely continue to do so. Email follow-ups about open online orders will also continue to emerge as the norm.

Implementations of blockchain technologies, like PureGold’s new gold-backed payment gateway, will enhance consumer access to e-commerce using cryptocurrency. Being a brick and mortar company with gold ATMs, gold minting factories and storefronts, PureGold also offers many offline ways to provide instant transactions for consumers. Whether mobile, desktop, or in person, maximum flexibility is offered.

The recent emergence of chat-bots like Drift and Intercom enable a site visitor to schedule a demo with a sales rep in seconds. Being able to do so prevents the need for back and forth email exchange. It also takes advantage of the currently attentive visitor before they become distracted or overwhelmed with other things.

4. No Excuse For Poor Web Design

Engineers have become better and there are new tools enabling novices to design quality-looking sites. In just a few clicks, developers and designers can now easily build content-ready, production sites for their products. Landing pages are critical components of a brand’s image and will largely determine the effectiveness of a company’s funnel. This trend is putting a greater emphasis on people that can design, build front-end sites, or even navigate a CMS like WordPress.

5. There Will Be A Greater Emphasis On Data (if that's even possible)

Marketers can look at more metrics than ever. These include open rates, time spent on pages, and how people interact with a page. This data can drive better decisions and keep marketing people from guessing. There has even been an emergence of machine learning in marketing. Machine learning can qualify leads and determine customer projected value.

Companies like Repux are using data and artificial intelligence to help businesses maximize their potential. On the Repux platform, businesses can sell anonymized data to developers for use with machine learning algorithms. Once optimized as intelligent applications, the applications can be sold back to businesses for better business decision making.

Larger brands will likely put more resources towards their branding, images and messaging because they can. Smaller brands do not have the budget or time for that. In the past, this meant that they were less effective. Now, though, smaller brands can test a handful of approaches quickly.
Then, they can use that data to inform their decisions.

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Wednesday, January 17, 2018

Globalization in the Age of Trump 01-18



Business leaders are scrambling to adjust to a world few imagined possible just a year ago. The myth of a borderless world has come crashing down. Traditional pillars of open markets—the United States and the UK—are wobbling, and China is positioning itself as globalization’s staunchest defender. In June 2016, the Brexit vote stunned the European Union, and the news coverage about globalization turned increasingly negative in the U.S. as the presidential election campaign progressed.
One week after Donald Trump’s inauguration, with fears of a trade war spiking, the Economist published a cover story, “The Retreat of the Global Company,” in which it proclaimed that “the biggest business idea of the past three decades is in deep trouble” and that “the advantages of scale and…arbitrage have worn away.” And Jeffrey Immelt, GE’s chairman and CEO, has talked about the company’s “bold pivot” from globalization to localization.
But is a mass retreat from globalization really the right approach for companies in these uncertain times? Or, short of packing up and returning home, should they focus on localization—that is, producing and even innovating where they sell—as the strategy of choice? Not according to my research. Recall that as recently as a decade ago, business leaders believed that the world was becoming “flat” and that global companies, unconstrained by country borders, would soon dominate the world economy. Those exaggerated claims were proven wrong. Today’s cries for a massive pullback from globalization in the face of new protectionist pressures are also an overreaction, in the other direction. While some of the euphoria about globalization has shifted to gloom, especially in the United States, globalization has yet to experience a serious reversal. And even if it did, it would be a mistake to talk about the end of globalization: The “rewind” button on a tape recorder shouldn’t be confused with the “off” button.
A full-scale retreat or an overreliance on localization would hamper companies’ ability to create value across borders and distance using the rich array of globalization strategies that are still effective—and will continue to work well into the future. Today’s turmoil calls for a more subtle reworking of multinationals’ strategies, organizational structures, and approaches to societal engagement. In this article, I address common misperceptions about what is—and isn’t—changing about globalization, offer guidelines to help leaders decide where and how to compete, and examine multinationals’ role in a complex world.

The Trajectory of Globalization

Doubts about the future of globalization began to surface during the 2008–2009 financial crisis. But as macroeconomic conditions improved, the gloom gave way to a murky mix of perspectives. For example, within the span of just three weeks in 2015, the Washington Post published an article by Robert J. Samuelson titled “Globalization at Warp Speed” and a piece from the editorial board called “The End of Globalization?”
In the face of such ambiguity, it is essential to look at the data. To see how globalization is actually evolving, Steven Altman and I compile the biennial DHL Global Connectedness Index, which tracks international flows of trade, capital, information, and people. The two index components of greatest business interest—merchandise trade and foreign direct investment—were hit hard during the financial crisis, but neither has suffered a similar decline since then. Trade experienced a large drop-off in 2015, but that was almost entirely a price effect, driven by plunging commodity prices and the rising value of the U.S. dollar. Updated data suggests that in 2016 foreign direct investment dipped, in part because of the U.S. crackdown on tax inversions. Complete data for 2016 is not yet available, but factoring in people and information flows will probably reinforce the conclusion that globalization has stayed flat or even increased.






What has nose-dived, however, is the tone of public discourse in the United States and other advanced economies. An analysis of media mentions for the term “globalization” across several major newspapers—the Wall Street Journal, the New York Times, and the Washington Post in the U.S. and the Times of London, the Guardian, and the Financial Times in the UK—reveals a marked souring of sentiment, with scores plummeting in 2016.





The contrast between the mixed-to-positive data on actual international flows and the sharply negative swing in the discourse about globalization may be rooted, ironically, in the tendency of even experienced executives to greatly overestimate the intensity of international business flows relative to domestic activity. In other words, they believe the world is a lot more globalized than it actually is.










Exaggerated perceptions about the depth of globalization—that is, how much activity is international versus domestic—come at a cost. In surveys I’ve conducted, respondents who overestimated the intensity of globalization were more likely to believe erroneous statements about international business strategy and public policy. When businesspeople think the world is more globalized than it really is, they tend to underestimate the need to understand and respond to differences across countries when operating abroad. In the public policy sphere, leaders tend to underestimate the potential gains from additional globalization and to overestimate its harmful consequences for society.

Surveys suggest that people also underestimate the breadth of globalization—that is, the extent to which international activity is distributed globally rather than narrowly focused. In a 2007 survey of Harvard Business Review readers, 62% of respondents agreed with the quote from Thomas Friedman’s best-selling book The World Is Flat that companies now operate on “a global, Web-enabled playing field that allows for…collaboration on research and work in real time, without regard to geography, distance or, in the near future, even language.” However, data shows that actual international activity continues to be dampened strongly by all those factors.
To counteract such “globaloney,” I offer two laws that govern, respectively, the depth and breadth of globalization:
  • The law of semi-globalization: International business activity, while significant, is much less intense than domestic activity.
  • The law of distance: International interactions are dampened by distance along cultural, administrative, geographic, and, often, economic dimensions.
These principles, set out in my book The Laws of Globalization, can be very helpful for strategy making—if they can be counted on to apply in the future. Given surging protectionist sentiments and possibly even a trade war, will they continue to hold? The best way of stress-testing them—at a time when the precise policies of the Trump administration and other governments are still unclear—is to look at the last time a major trade war broke out, in the 1930s, which led to the largest reversal of globalization in history. Two major lessons, corresponding to the two laws of globalization, stand out.
The first lesson is that although trade dropped precipitously in the 1930s, it did not dry up entirely. The collapse that began in 1929 was staggering, and by early 1933, trade flows had plummeted by two-thirds. That said, the drop-off in value reflected a fall more in prices than in quantities, which declined by less than 30%. Even in the wake of the collapse, trade volumes continued to be far too large for business strategists to ignore.
The second lesson is that distance of various sorts continued to dampen international business activity. For example, from 1928 to 1935, the relationship between trade flows and geographic distance barely budged. The beneficial effects of a common language and colonial ties remained powerful: Country pairs with such ties continued to trade about five times as much with each other as pairs without such ties, all else being equal. The net result was that the trading partners with whom countries (or groups of countries) did most of their business before the crash remained largely unchanged afterward.
Getting back to the future: If global trade didn’t screech to a halt in the 1930s, it’s reasonably safe to say that it won’t in the 2020s, either. In fact, analyses of what a trade war under Trump might look like suggest much smaller declines in trade than occurred in the 1930s. Moody’s Analytics estimates that if the United States were to impose proposed tariffs on China and Mexico and those two countries retaliated in kind, that and other factors would shrink U.S. exports by $85 billion in 2019. That’s only about 4% of total U.S. exports in 2015. Of course, a wider trade war would have a more significant effect, but it is very unlikely that the consequences would be as dire as in the 1930s.
Similarly, if the breadth of trade didn’t change much despite the drastic declines in depth during the Great Depression, it probably wouldn’t change much in the event of a trade war today. It is worth adding that with many more independent countries now, as well as more vertically fragmented supply chains, the estimated effects of geographic distance on merchandise trade are actually larger than they were in the 1930s.

Where to Compete

If cross-border interactions in the aggregate are unlikely to fade away, what is the rationale for individual multinationals’ pulling back? The recent Economist article on the retreat of global companies, which has stirred significant discussion, pointed to the performance problems they have experienced. But the declines over the past three to four years occurred in an environment of plunging commodity prices, dropping demand for globalization-related services, and, for U.S. companies, shifts in exchange rates—factors that clearly played outsize roles in the performance numbers. And longer-term declines over the past decade coincide with a period in which globalization actually slowed down.
To argue that poor performance problems over this period should force reconsideration of multinationalization would be like arguing that Singapore, the most deeply connected country in the world according to the DHL Global Connectedness Index, should pull back from globalization because of the growth problems it has experienced since the financial crisis. The latest report of Singapore’s official Committee on the Future Economy dismisses that notion, saying that globalization through trade, capital, and knowledge flows is still the future, as far as Singapore is concerned. And even in countries much less dependent on exports than Singapore is, a wholesale pullback from globalization would be counterproductive.
Even when economic conditions are favorable and globalization is advancing rapidly, as was the case several decades ago, multinationals can face performance issues. My 2003 HBR article, “The Forgotten Strategy,” notes that between 1990 and 2001, Fortune Global 500 companies consistently posted lower average returns on sales for their foreign operations than for their domestic ones. Given the difficulties implied by the law of distance, multinationalization has always been an option, not an imperative. Some firms—and industries—clearly overdid it, especially in the years leading up to the financial crisis.
What’s lacking in much of the debate today is the notion of contingency: a case-by-case approach in which a globalization-related move is evaluated on its own merits rather than subjected to some sweeping injunction about whether to go forth and globalize or to come back home. That said, many multinational companies do need to pay renewed attention to where they compete—in other words, to market selection.
They must also resist the idea that a truly global company must compete in all major markets. Some 64% of the respondents to the 2007 HBR survey agreed with this (non)dictum, yet an analysis of internal financial data from 16 multinationals around that time indicated that eight of them had large geographic units that destroyed value after their financing costs were taken into account. Such problems still persist. Toyota, for example, seems to be the only major competitor in the highly globalized auto industry that has managed to build up significant market share in Japan, North America, and Europe and in key emerging economies—while remaining highly profitable. By contrast, most major automakers would be better served by following the example of GM, which shed its loss-making European operation, Opel, in March 2017.
Recent data on companies ranked among the top 100 with the most assets located outside of their home countries tells a similar story. While these companies tend to operate in dozens of countries, their top four markets—including their home market—account for about 60% of their revenues and probably a larger slice of total profits. And only a single-digit percentage of the Fortune Global 500—the world’s largest firms by revenue—earn at least 20% of their revenue in each of the “triad” regions of North America, Europe, and Asia-Pacific.

In sorting out which markets to focus on, it’s important to note that the law of distance applies to foreign direct investment as well as trade. Although FDI is less sensitive to geographic distance than trade is, I estimate the effect of a common language and a colony-colonizer link to be similar and FDI to be more sensitive to differences in per capita income.
So as companies today weigh their options, they should look for opportunities where they can find cultural, administrative/political, geographic, and economic affinities. This resonates even more strongly as we recall that country relationships became even more important during the 1930s. As the political environment shifts, business leaders need to keep a careful eye on how their home countries are realigning their international ties, and engage in their own corporate diplomacy.
Remember too that staying at home is an option. Only about 0.1% of the world’s firms are multinationals, although since multinationalization is highly skewed toward larger firms, this greatly understates their overall impact. (Their foreign affiliates generate 10% of global GDP, and the multinationals themselves account for more than 50% of world trade.) For companies based in large emerging economies, focusing on the domestic market, where they enjoy home court advantage as well as rapid growth, can be a particularly attractive proposition.
Leaders must resist the idea that a global company has to compete in every market.
Of course, trade can occur without multinationalization, and this is what some tout as the wave of the future: The Economist points to “a rising cohort of small firms using e-commerce to buy and sell on a global scale.” But e-commerce is still significantly less internationalized than off-line commerce. And in light of changes brewing in the policy environment, this seems like a particularly inauspicious time to think that one can go global just by setting up a website or joining an online platform.

How to Compete

If you conclude that your company should continue to do business in a variety of markets, you still need to figure out whether to change the type or mix of strategies that you use in response to protectionist pressures. At a high level, globalization strategies have three components, as described in my 2007 book, Redefining Global Strategy.
Companies use adaptation when they want to adjust to cross-country differences in order to be locally responsive. They use aggregation to achieve economies of scale and scope that extend across national borders. And arbitrage strategies are used to exploit differences, such as low labor costs in one country or better tax incentives in another.
How companies should use these three strategies will change somewhat in a protectionist world—but perhaps less than you’d think. Take adaptation. Jeffrey Immelt isn’t alone when he talks of his company’s “bold pivot” away from aggregation and the importance of “localizing” in today’s environment. Firms should look for opportunities to amp up their adaptation efforts, because becoming more responsive to differences can help reduce the impact of protectionism.
The most obvious way for a company to adapt is to vary products, policies, market positioning, and so on to suit local markets. However, each variation increases costs and complexity. Therefore, smart adaptation typically involves limiting the amount of variation as well as finding ways to improve the effectiveness and efficiency of any changes that are introduced. For example, companies can design common platforms upon which local variants are offered. Or they can externalize some of the costs of adaptation via franchising, joint ventures, or other types of partnerships.
But while more adaptation may make sense, multinationals should not automatically put it above all else—doing so would only undercut their sources of competitive advantage relative to local competitors. Global companies—especially those from advanced economies—typically justify their cross-border strategies primarily on the basis of aggregation. In the most classic cases, they invest in intangible technological or marketing assets that they can scale across national borders. Those advantages normally have to be pretty large in order to overcome the home court advantage of local competitors. The economic rationale for aggregation won’t evaporate for multinationals that have built a healthy, profitable business in foreign markets—even if some countries make it more expensive to operate within their borders. Companies that have operations in markets where they’re only marginally successful, on the other hand, may need to retrench.
Turning to arbitrage, the opportunities for vertical multinationals to globalize on the supply side rather than on the demand side have narrowed somewhat in recent years, but they still remain large. Even with rising prosperity in large emerging markets, U.S. GDP per capita is still seven times that of China, and 33 times that of India. Differences in tax regimes across countries are not going away either, and will continue to provide arbitrage opportunities. According to the OECD, the dispersion of corporate tax rates across countries has barely changed since 2007, and progress at curbing tax havens has been slow. Furthermore, cross-country differences in safety, health, and environmental standards continue to persist as well—although exploitation of these differences raises ethical concerns.
Multinationals coming out of emerging markets tend to get their start from advantages rooted in arbitrage—competing abroad on the basis of low costs at home. This strategy continues to be the engine that drives the growth and profitability of India’s offshore IT services industry—which inspired Friedman’s The World Is Flat, kicking off a wave of interest in arbitrage strategies. More than a decade later, programmers’ salaries in India are still just a fraction of those in the United States, and cost reduction remains the top reason companies choose to outsource. The largest India-centric vendors have far outstripped their Western competitors in terms of both growth and profitability, and as of June 2016 the top four India-centric vendors enjoyed market valuations more than 50% larger than those of their top four Western competitors.
As companies from advanced and emerging countries joust for global leadership, each has to shore up its traditional weakness—for incumbents, that’s arbitrage; for insurgents, it’s aggregation. For example, developed-world incumbents in IT services, such as Accenture and IBM, have expanded their workforces in India, while Indian companies are trying to strengthen their brands and technological capabilities.
Returning to GE, Immelt’s pivot toward localization does imply a boost to its adaptation strategy. But GE—like most other multinationals—cannot give up on aggregation or arbitrage. GE’s aggregation-based advantages are what underpin its ability to compete across 170 countries. Its $5.5 billion R&D machine yields world-beating technological innovations, its $34 billion brand value opens doors everywhere, its famous management-training programs both attract and cultivate talent, and its scope across products, services, and geographies all contribute to GE’s immense cross-border aggregation potential. And while Immelt’s remarks shrewdly downplay wage arbitrage as “what GE did in the 1980s,” in contrast to its current focus on selling more abroad, arbitrage has become sufficiently ingrained at the company over the past few decades that it will probably not disappear and will continue to be part of its globalization strategy. In my view, GE’s “localization” strategy is best understood as one that retains a core strength in aggregation while toning down the company’s prior emphasis on arbitrage and becoming more adaptive.

Engaging with Society

Along with where and how to compete, questions about how to engage with society are becoming increasingly prominent on business leaders’ agendas. Except in highly regulated industries, companies have historically treated interactions with governments, media, and the public as an afterthought in setting strategy. But now, as Martin Reeves of BCG points out, “In many cases companies are seeing bigger impacts from political and macroeconomic factors than from competitive considerations.” Those factors, he says, include Brexit-driven exchange rate movements, share price fluctuations in response to policy pronouncements, and the cost of changing investment plans in light of anticipated shifts in trade policy. I would add to the list the rise of NGOs, the proliferation of social media, and increases in anti-globalization sentiment.
Companies are constrained in their responses to these developments by a range of factors. First of all, the backlash against globalization is also—in part—a backlash against big business. The general reputation of business is at an all-time low. In a recent survey, the Pew Research Center asked respondents in the U.S. how much people in 10 occupations contributed to the well-being of society. Business executives ranked next to last, ahead only of lawyers. Just 24% of respondents said they thought business leaders contributed “a lot.” The 2017 Edelman Trust Barometer also reports an all-time low for CEO credibility. And companies’ decisions about how to deploy the reputational capital that they do possess are complicated by tensions between a country’s citizens and its government—Uber CEO Travis Kalanick ran into problems with public perception when he joined Trump’s business advisory council, for example—as well as by uncertainties about how the broader environment will evolve.
In such a context, just speaking up more about social issues—as business leaders today are often instructed to do—is no panacea. While it is hard to offer simple instructions about how to cope with these complexities, the law of semi-globalization does suggest one injunction and one insight. First the injunction: Falling in line with what governments want wherever a company operates is unlikely to be a sustainable strategy. Multinational companies need to craft governmental and societal agendas that are both localized and linked across countries. Anti-globalization pressures require that multinationals deliver more local benefits—and communicate about them—in the countries where they operate. Such efforts must go well beyond compliance to include contributions in the form of jobs, technology, and so forth.
The backlash against globalization is also—in part—a backlash against big business.
Of course, there are dangers to shifting too far toward localization. Consider how IBM responded to the rise of the Nazi regime in Germany. Rather than pulling back—even as it became clear that the census IBM was supporting was being used to identify Jews for persecution—IBM sought to grow its business with the Nazi government. In 1937, then-CEO Thomas Watson was awarded—and accepted—a medal from Hitler for “service to the Reich.” One would hope that such a strategy would not even merit consideration today.
The law of semi-globalization affords an important insight as well: Addressing much of our current malaise—including but not confined to anti-globalization sentiment—requires domestic policy changes rather than the closing of borders. For example, one of the principal complaints about globalization today is the sense that it has contributed to rising income inequality and that a large swath of the population in advanced economies has been left behind. In the U.S., income inequality has recently risen to levels last seen in the 1920s, and other countries, especially developed ones, have registered similar, if less dramatic, increases. Meanwhile, corporate profits are running close to their highest historical levels.
The widespread perception that globalization is primarily to blame for this problem, however, is empirically implausible. Most research suggests that technological progress and (in the United States) the decline of unions have been bigger contributors to inequality than globalization. Corroboration is supplied by real-world examples: If the Netherlands can preserve a more reasonable income distribution despite having a trade-to-GDP ratio six times that of the United States, it seems odd to blame globalization for the much higher level of inequality in the U.S. economy. And even if one is inclined to point fingers at globalization, it is clear that protectionism is a much more expensive solution than government safety nets, increases in the minimum wage, changes in tax policy, job-training programs, and the like. Such policies are not typically favored by big business, so corporate voices advocating them make a powerful statement. Furthermore, closing borders does nothing to prepare a country to deal with the automation-related threats to jobs that dominate the debate about the future of work.
My research into the 2011 book, World 3.0: Global Prosperity and How to Achieve It, offers an in-depth evaluation of the various harms attributed to globalization. (I expected the present backlash to arrive several years before it did.) Some, such as the risks associated with international imbalances in trade and investment, are indeed real and significant. Most others, however, turn out to be overblown in relation to actual levels of international integration. For example, the contribution of international air transportation to energy-related greenhouse gas emissions is only one-tenth as large as British air travelers estimated in a survey. To deal with global warming, it would be far more effective to tackle bigger sources such as housing or driving. My research suggests that international openness should be coupled with targeted domestic policies in addressing such side effects as globalization does have.
That perspective is, of course, the opposite of President Trump’s apparent preference for domestic deregulation and international intervention, which brings me to my last point—which may seem politically partisan but is rooted in the common notion that a company’s market and nonmarket strategy should be in alignment. If your company is or may eventually be global, it’s not a good idea to actively support policies that build up barriers to trade and capital flows, make people less mobile, and delegitimize the idea that companies can contribute to the well-being of people in more than one country—even if all you care about is shareholder value. Over the long run, companies that rely heavily on sourcing from abroad (such as Walmart) and those that export far more than they import (such as GE) would benefit from joining forces to oppose protectionism.

CONCLUSION

In his classic 2006 Foreign Affairs article Samuel Palmisano, then chairman and CEO of IBM, pointed out that 150 years ago, companies that crossed borders engaged mostly in trade, but by the early 1900s, they had started to invest in localizing production. He also proclaimed the recent emergence of a new corporate form, the globally integrated enterprise, for which “state borders define less and less the boundaries of corporate thinking or practice.”
From today’s perspective, that seems too rosy by half. But there is some good news for those tasked with leading multinational companies. First, the global corporation never became nearly as integrated as Palmisano prophesied, so the amount of change required if globalization does go into reverse is less than people might think. Second, it’s still unclear whether a retreat from globalization will occur: International activity has stagnated in recent years but has not fallen off significantly. And third, even if globalization suffered a violent reversal similar to that experienced at the beginning of the 1930s, the world would still remain more globalized in terms of trade and foreign direct investment than it was in the 1920s, let alone in the 19th century. So reverting to the multinational structure of 100 years ago or the trade-based structures of 150 years ago strains plausibility. Globalization strategy and practice have advanced well beyond the prescriptions those historical models would imply, and leaders would be ill-served by going backward.